Deep Brain Stimulation for Parkinson’s Disease: Case-Based Insights and Clinical Implications: Deep Brain Stimulation for Parkinson's

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia, as well as a range of nonmotor manifestations. While pharmacotherapy remains the mainstay of PD management, many patients experience inadequate symptom control or adverse effects, prompting the exploration of alternative treatments. Deep brain stimulation (DBS) has emerged as a promising therapeutic option, offering targeted neuromodulation to alleviate motor symptoms and enhance patients’ quality of life. This study explores the clinical outcomes of DBS treatment in three PD patients, offering insights into the efficacy, safety, and challenges associated with this intervention. Through the analysis of tremor reduction, functional capacity improvement, and complications following DBS treatment, we aim to illuminate the real-world implications of DBS in clinical practice and contribute to the growing evidence supporting its use in patients with refractory PD. Ultimately the findings underscore the importance of individualized treatment plans and multidisciplinary care to achieve optimal outcomes for PD patients.